Vol. 10, Special Issue 8 (2021)

Author(s):
Dr. Manoj Kumar and Dr. Abhishek Kumar

Abstract:
The objective of the present study was to assess the in-vitro antimicrobial efficacy of Punica granatum rind and Psidium guajava leaf extract on enteropathogenic Escherichia coli and to evaluate its effectiveness in the treatment of colibacillosis in calf. The experiment was conducted at Department of Veterinary Medicine, College of Veterinary Science and Animal Husbandry, Birsa Agricultural University, Kanke Ranchi. A total no. of 60 colibacillosis positive calves (Escherichia coli positive) and six (06) clinically normal healthy calves (Healthy control) were taken to investigate the haemato-biochemical profiles. E. coli was isolated from the colibacillosis affected calves and the animals found positive were used for the study of haemato-biochemical profile. Faecal sample were cultured on MacConkey and EMB agar to diagnose E. coli. Analysis of blood and serum samples of the colibacillosis affected calves revealed significant increase in Haemoglobin, Total erythrocyte count, Total leukocyte count, Blood urea nitrogen, Total serum protein, Serum creatinine, and Serum potassium, while significant decrease in Blood glucose and Serum sodium. However, no significant changes were observed in Alanine transaminase.