Vol. 10, Special Issue 6 (2021)

Author(s):
Kalyani Thakur, VM Dhoot, GR Bhojne, SV Upadhye and AP Somkuwar

Abstract:
Kidney disease is more common in canine population today. Hence the need of medications for kidney diseases also increased recently. The purpose of the present study is to assess the efficacy of probiotics in the management of chronic kidney disease in dogs. A probiotic formulation of selected microbial strains administered through oral route in dogs with chronic kidney disease may extend renoprotection via intra-intestinal extraction of toxic waste solutes. The aim behind the study is to prevent the production of major damaging uremic toxins by targeting the process of bacterial protein fermentation in the gut and improving renal function. Dogs with chronic kidney disease have been shown to experience a disturbed gut flora, which promotes the increased production of those harmful toxins. By supplementing with a specific combination of bacteria viz. Streptococcus thermophilus, Lactobacillus acidophilus, and Bifidobacterium longum (probiotics) and beneficial fibre i.e. psyllium (prebiotics), to support the growth of the good bacteria, it improves the health of the gut, suppressing the growth of harmful bacteria, thus decreasing the production of the toxins.