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Vol. 10, Special Issue 5 (2021)

Exploration of Mukia maderaspatana as promising topical herbal preparation for cutaneous warts in cattle

Author(s):
MJ Raja and A Jagadeeswaran
Abstract:
Bovine cutaneous papillomatosis (warts) is a contagious disease caused by Bovine Papilloma Virus (BPV) with proliferative and benign neoplasms on the skin in cattle. Generally, warts reduce the aesthetic value of the skin and also occurrence on teats and udder with infection leads to development of mastitis. Surgical and medicinal treatments including homeopathy remedies are available for the treatment of warts in cattle, but with limited cure. In recent days, awareness of using herbal drugs is increasing because of their promising results. Many medicinal herbs have been known for their anti-wart effects, but their effectiveness in livestock is not yet explored much with proper validation and screening. Hence, the present study was undertaken to explore the anti-wart effect of Mukia maderaspatana in cattle.
Collection and identification of herb, preparation of leaves and whole plant extracts, phytochemical analysis and selection of appropriate base for the preparation of ointment was done. A dose fixation trial with 1%, 2%, 5% and 10% of herbal ointment was conducted in clinical cases of warts in bovines. Based on the results, 10% of herbal ointment was selected as the dose for the treatment of warts in clinical cases of cattle. The results of the study showed enriched phytochemicals in whole plant powder than leaves crude powder. White soft paraffin was selected as base for the ointment preparation based on the scores on physical properties and practical utility.
The clinical study results revealed significant anti-wart effect at 10% of this herbal ointment. Animals treated with 10% Mukia maderaspatana ointment showed results as complete, moderate and no cure as 60%, 20% and 20% respectively. Enriched phytochemicals like tannins, potential therapeutic properties like antiviral, antibacterial, anti-haemorrhoidal, vasoconstrictor activities, and other properties like inhibition of lipid peroxidation and coagulation of proteins could be the reasons for the anti-wart effect of this herb and the same can be compared with other existing treatment procedures and explored further in detail.
Pages: 653-659  |  424 Views  190 Downloads
How to cite this article:
MJ Raja and A Jagadeeswaran. Exploration of Mukia maderaspatana as promising topical herbal preparation for cutaneous warts in cattle. The Pharma Innovation Journal. 2021; 10(5S): 653-659.

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