Vol. 8, Issue 11 (2019)

Author(s):
Mylaram Jeevana Latha, M Lakshman, A Anand Kumar, A Gopal Reddy and D Pramod Kumar

Abstract:
Hexavalent chromium salts have been recognized as occupational health hazard for more than 160 years. It is a potent toxic agent. It has been found to be carcinogenic in human and animals. Hexavalent chromium is generally considered 1000 times more toxic than trivalent chromium. The experiment was conducted to study the embryonal toxicity in female wistar rats by inducing hexavalent chromium at the rate of 500 parts per million in the form of potassium dichromate in drinking water orally for three months and also to pregnant animals, with the protective and ameliorating agents like vitamin C and emblica officinalis (E. officinalis) respectively. Foetuses were collected by sacrificing pregnant rats from all six groups for the purpose of radiographic study. The fetuses from all groups were subjected to radiographic study. The embryos from the toxin group revealed mild subdermal haemorrhages over abdomen region, ill developed fetuses when compared to the morphological features of control, protective and ameliorative group embryos.