Vol. 7, Issue 11 (2018)

Author(s):
Traoré Sidiki, Ouédraogo Salfo, Yoda Jules, Traoré Tata Kadiatou, Traoré Aristide, Lompo Marius, Kini Felix, Ouédraogo Sylvin and Semdé Rasmané

Abstract:
Two kinds of syrups based of Parkia biglobosa trunk's barks of were prepared and evaluated. One was a dry syrup, prepared by using Tween 80 as a wetting agent, and the other was a suspending syrup. The Physicochemical Analysis, microbiological and Storage Stability from syrups were studied, and both syrups showed the. The syrups had good appearance without deposit, sweet taste with a bitter aftertaste, a dark red color and a faint odor. The chemical composition of the suspending syrups after 3 months years of storage under the conditions studied was always similar and therefore homogeneous composition. These analyses showed insignificant physicochemical alteration of syrups in the storage conditions used. Assessments of bacterial contamination of syrups showed absence of Salmonella and coliforms. These results are in line with the recommendations of the European Pharmacopoeia 6.0 for oral preparations containing naturally occurring raw materials. There is no incompatibility between the selected excipients, extracts and the packaging materials. The trunk's barks extracts of Parkia biglobosa has the potential for making stable pharmaceutical syrup.