Vol. 5, Issue 8 (2016)

Author(s):
Kazi Ashfak Ahmed Chowdhury, SM Zahid Hosen, Mohammad Nazmul Islam, Irfanul Huq, Md. Adnan, Md. Nazim Uddin Chy, Md. Imtiazul Kabir, Reedwan Bin Jafar Auniq, Md. Rakib Uddin, Mohammed Shoibe and Mohammad Asraful Gani Chowdhury

Abstract:
The study was aimed to evaluate the cytotoxic and thrombolytic activity of methanol extract of Musa paradisiaca. The cytotoxic activity of the crude extract was determined by using brine shrimp lethality bioassay and LC₅₀ values of the sample were 22.336 ± 0.41μg/ml whereas for standard vincristine sulfate was 8.50 ± 0.16μg/ml as a positive control. In thrombolytic activity using in vitro clot lysis method, the plant’s extract showed (46.26 ±1.54%) clot lysis as compared to standard streptokinase (67.32±0.34%).