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Vol. 12, Special Issue 8 (2023)

Comparative efficacy of Nemocid, Albomar and Alfanil in cases of spontaneous Toxocariasis at dog ward, teaching veterinary clinical complex, WBUAFS, Kolkata, West Bengal, India

Author(s):
Sarmistha Debbarma, Nishith Ranjan Pradhan and Debaki Ghosh
Abstract:
Introduction: Toxocariasis is a worldwide parasitic infection and dogs serve as the most important definitive hosts for Toxocara canis: a causative agent of human toxocariasis and one of the most widespread zoonotic helminths worldwide.
Materials and methods: For this study out of 24/42 positive pups irrespective of age, sex and breeds were randomly selected. Total 30 pups divided into 5 groups of 6 puppies as: Group 1: Healthy control, Group 2: Untreated control, Group 3: Nemocid (Pyrantel pamoate) suspension @50 mg/kg bw/d orally as single dose, Group 4: Albomar (Albendazole) suspension @50 mg/kg bw/d for 3 days orally and, Group 5: Alfanil tablet (combination of Praziquantel, Pyrantel embonate and Oxantel embonate) @1 tab/10 kg bw/d orally as single dose. Animals were under observation for 9-months from treatment dosing and tests for clinical, haematological, biochemical and faecal examinations.
Results: Overall incidence of Toxocara canis infection in and around Kolkata city was 38.18%, with higher incidence during the monsoon (64.29%), sex-wise in males (66.67%), incidence-wise in age group 1-3 months, breed-wise in non-descript puppies (61.90%), and a decrease of haematological and biochemical parameters was observed in the pre-treatment infected pups. All three anthelmintics were found effective against the Toxocara spp. infection in the pups.
Conclusion: Considering the best efficacy, the combination of Praziquantel, Pyrantel embonate and Oxantel embonate at a dose rate of 1 tab/10 kg b.wt. as single dose can suitably be recommended for treatment of toxocariosis in pups.
Pages: 1800-1807  |  186 Views  95 Downloads
How to cite this article:
Sarmistha Debbarma, Nishith Ranjan Pradhan and Debaki Ghosh. Comparative efficacy of Nemocid, Albomar and Alfanil in cases of spontaneous Toxocariasis at dog ward, teaching veterinary clinical complex, WBUAFS, Kolkata, West Bengal, India. The Pharma Innovation Journal. 2023; 12(8S): 1800-1807.

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