Dexmedetomidine-butorphanol premedication, ketamine-diazepam induction and isoflurane maintenance anaesthesia for surgical management of acute abdomen in dogs
Vishnugurubaran D, Kathirvel S, Dharmaceelan S, Saravanan S and Sureshkumar V
Twelve dogs of different age and sex presented with clinical signs of acute abdomen like abdominal pain, distension, cessation of defecation and urination, oliguria, dystocia etc. were selected for the study. All the animals were premedicated with dexmedetomidine and butorphanol intravenously. The anaesthesia was induced with ketamine-diazepam intravenously and maintained with isoflurane using variable vaporizer setting. The heart rate, respiratory rate, temperature, SPO2, EtCO2, tidal volume, minute volume, systolic blood pressure, diastolic blood pressure and mean arterial pressure were monitored through out the anaesthetic period. The qualities of anaesthesia like time for intubation, Fresh gas flow, average vaporizer setting, time for extubation, time for head raising, time for sternal recumbency and time for unassisted standing were recorded. Haematology and serum biochemical analysis were done peri-operatively, intra-operatively and post-operatively. The heart rate was initially decreased after premedication and after induction, but because of the positive ionotropic properties of ketamine the heart rate was well maintained during the anaesthetic maintenance period. The respiratory rate and body temperature was decreased significantly after premedication to throughout the period of anaesthesia. The SpO2, EtCO2, tidal Volume and minute volume were maintained well during the anaesthetic period. There was no significant change in haematological and serum biochemical parameters during different stages of anaesthesia. The anaesthetic protocol employed in the present study proved to be safe for dogs with acute abdomen as there was no anaesthetic complications.
How to cite this article:
Vishnugurubaran D, Kathirvel S, Dharmaceelan S, Saravanan S and Sureshkumar V. Dexmedetomidine-butorphanol premedication, ketamine-diazepam induction and isoflurane maintenance anaesthesia for surgical management of acute abdomen in dogs. The Pharma Innovation Journal. 2023; 12(8S): 820-824.