Vol. 12, Special Issue 7 (2023)

Author(s):
Rahul Paul, Basanta Saikia and Analisha Debbarma

Abstract:
The present study was undertaken in 18 dogs with elective surgery (castration, spaying etc.) to evaluate the effect of propofol, Ketofol and etomidate as induction agents on Haemato-biochemical parameters in glycopyrrolate premedicated dogs maintained with isoflurane. The animals were randomly divided into three groups viz. group P, KP & E, comprising six animals in each group. All the animals of the three groups were premedicated with glycopyrrolate @ 0.01 mg/kg IM, 10 minutes prior induction. Propofol @ 6mg/kg IV, Ketofol @ 4mg/kg and etomidate @ 3mg/kg was administered as induction agent in group P, KP and E respectively. Maintenance of anaesthesia was carried out by using isoflurane in all the animals in all three groups. Parameters of Haemato-biochemicalprofile were studied at (baseline) 0 min and thereafter 5-, 15-, 30-, and 60-minutes time interval after induction.