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Vol. 12, Special Issue 7 (2023)

Gene editing: Revolution for genome modification and its scope in healthcare research

Author(s):
Nishant Ranjan, Pallavit Lata, Shristi Tanaya, Shivam Shekhar, Arpit Raturi, Rishav Kumar, Dheetan Parthsarthi, Vijeta Jha, Sushant Kumar and Viabhav Kumar Upadhayaya
Abstract:
Genome editing is a technique that has opened the door for a new concept in which we can manipulate the genome sequence for different purposes. Generation of specific pre-planned changes for genome manipulation includes double-stranded breaks. The double-stranded breaks use the intrinsic repair mechanism of the cell. Four major methods for inducing site-specific double-stranded breaks which are CRISPR, TALENs, ZFN, and Mega nuclease. Out of these CRISPR is the most recent and easy-to-use technique for genome editing. It has provided powerful tools for the precise modification of genetic material. Genome editing has a wide range of purposes in different sectors including healthcare, therapeutics, agriculture, etc.
Pages: 280-284  |  367 Views  123 Downloads
How to cite this article:
Nishant Ranjan, Pallavit Lata, Shristi Tanaya, Shivam Shekhar, Arpit Raturi, Rishav Kumar, Dheetan Parthsarthi, Vijeta Jha, Sushant Kumar and Viabhav Kumar Upadhayaya. Gene editing: Revolution for genome modification and its scope in healthcare research. The Pharma Innovation Journal. 2023; 12(7S): 280-284.

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