Vol. 12, Special Issue 11 (2023)

Author(s):
Deepan G, Bhanu Rekha V, Ajay Kumar VJ, Nithya Quintoil M, Gidla Veera Venkata Satyanarayana and Killada Abhiram Naidu

Abstract:
Klebsiella pneumoniae poses a significant threat to public health, as it is a leading cause of multidrug-resistant infections in hospitalized patients. This opportunistic pathogen is known to transfer antimicrobial resistance genes to other bacteria, exacerbating the issue of antibiotic resistance. Despite extensive research on K. pneumoniae, its ecology, pathogenicity, and population structure remain elusive. However, one aspect that has been overlooked is its ability to cause food-borne infections. While the reports on food-borne K. pneumoniae are limited, it’s potential to cause severe infections such as liver abscesses, septicaemia, and diarrhea in humans, as well as mastitis, urinary tract infections, and respiratory infections in animals, cannot be underestimated. The presence of Klebsiella pneumoniae in food is a concern because contaminated food can be a potential source of infection for humans. Foodborne transmission of Klebsiella pneumoniae can occur through the consumption of contaminated foods, such as raw vegetables, meat, and dairy products. The presence of multidrug-resistant strains of K. pneumoniae in the food chain can contribute to the spread of antimicrobial resistance, particularly among clinically relevant bacteria. In fact, beta lactamase and carbapenamase producing Enterobacteriaceae, including K. pneumoniae, have been classified as critical priority pathogens by the World Health Organization, highlighting the urgent need for new antimicrobial treatments. To combat AMR and K. pneumoniae infections, a comprehensive one health approach is necessary. Experts from medical, veterinary, pharmacology, microbiology, and the environment should work together to develop new strategies for preventing and treating infections. The development of novel antibiotics, antibiotic stewardship programs, and monitoring and surveillance efforts are also essential components of this approach.