Vol. 11, Special Issue 9 (2022)

Author(s):
Pushpa Lohani, Srishti Joshi, Jeetendra Singh Bohra, Anuj Kumar and Keshav Singh

Abstract:
Cancer is characterized as abnormal growth in cells which have managed to evade central endogenous control systems. This abnormality can arise from either genetic or epigenetic change. A cascade of signaling pathways are responsible for cell growth, division and death. Dysfunctioning in these pathway leads to overexpression or underexpression of some molecules fuel cancer proliferation. Due to rapid technological advances in last few years, it is possible to analyze the signaling pathways involved in cancer proliferation and therefore simpler diagnostic in a shorter period of time. PI3K-Akt and Ras-EKT pathways are two major pathways which are to be examined for cancer treatment.