Vol. 11, Special Issue 8 (2022)

Author(s):
Sajida Bano, Samar Sarkar, Chandan Lodh and Subhasis Batabyal

Abstract:
The study was undertaken in 30 clinical cases of dogs diagnosed with osteoarthritis of various joints, and free of other concurrent neurological, metabolic and infectious diseases along with six healthy control dogs. Of these dogs, 36 dogs were divided into six groups of 06 dogs each. Animals of Group I were treated with collagen peptide orally at the dose rate of 1.0-2.0 mg/kg bwt and along with a combination of Sunthi (0.08gm/kg bwt), calcium (25mg/kg bwt) and Vitamin D (0.02-0.03mg/kg bwt) once daily for 60 days. The second groups were treated with meloxicam orally at the dose rate of 0.2 mg/kg body weight, once daily for 7 days along with a combination of collagen peptide (1.0-2.0 mg/kg bwt) for 60 days. The third group was treated with Herbal component like Sunthi at a dose rate of 0.08 gm/kg body weight orally, daily for 60 days. The fourth group was treated with Glucosamine sulphate (25mg/kg bwt) and Chondroitin Sulphate (20mg/kg b wt) orally, daily for 60 days. The fifth group was treated with calcium (25mg/bwt) and Vitamin D (0.02-0.03mg/kg bwt) orally, daily for 60 days. The sixth group was kept as healthy control. The parameters studied included incidence of Bone Related Disorders in dogs. In osteoarthritis sex wise incidence, breed wise incidence, age wise incidence, Joint wise incidence, radiographical examination, haematological parameters, serum biochemical parameters were seen. Group I animals showed significant reduction in lameness on day 60 which could be attributed to the effect of collagen peptide, sunthi, calcium and vitamin D in providing relief to osteoarthritic pain as compared to other four groups which showed very mild improvement and also there was significant decrease (P<0.01) in uric acid and C-RP. Radiography and clinical sign was the used in diagnosis of OA. Hence, Group I is the better as compared to other groups.