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Vol. 11, Special Issue 7 (2022)

Effect of dexmedetomidine/midazolam - ketamine anaesthesia on physiological and haematological parameters in dogs undergoing elective ovariohysterectomy

Author(s):
Anju Poonia, Deepak Kumar Tiwari, Ashok Kumar, Sandeep Saharan, Neeraj Arora, Gaurav Kumar and Maneesh Sharma
Abstract:
The present study was conducted on 28 female dogs irrespective of age, breed and body weight brought for elective ovariohysterectomy which were randomly divided into two groups comprising of 14 animals in each group. Sedation was achieved by administration of Dexmedetomidine and Midazolam in group-I and II, respectively. Heart rate was decreased significantly in group-I, while increased significantly in group-II after sedation. Respiratory rate and rectal temperature showed significant decline after sedation in both the groups. Haemoglobin and TEC values were decreased significantly after pre medication and afterwards and there was non-significant decrease at the end of surgery in group-II as compared to group-I. In both the groups, there was non-significant decrease in TLC and PCV values at different time intervals. From the present study, it was concluded that Midazolam/Dexmedetomidine anaesthetized with ketamine provide adequate sedation in the dogs undergoing elective ovariohysterectomy surgery. Midazolam/ Dexmedetomidine provides better haemodynamic and respiratory stability when used as a pre-anaesthetic for induction with ketamine in the dogs undergoing elective ovariohysterectomy surgery.
Pages: 3237-3242  |  390 Views  236 Downloads
How to cite this article:
Anju Poonia, Deepak Kumar Tiwari, Ashok Kumar, Sandeep Saharan, Neeraj Arora, Gaurav Kumar and Maneesh Sharma. Effect of dexmedetomidine/midazolam - ketamine anaesthesia on physiological and haematological parameters in dogs undergoing elective ovariohysterectomy. The Pharma Innovation Journal. 2022; 11(7S): 3237-3242.

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