Vol. 11, Special Issue 7 (2022)

Author(s):
Karunesh Kumar Dubey, SP Yadav, Gulab Chandra, DS Sahu, Rajkumar, Prem Sagar Maurya, Deepak Singh and Kartik Tomar

Abstract:
This study assessed the effect of dietary supplementation of silymarin and nano-zinc on protein metabolism of Sahiwal Calves. Twenty-eight 6-15 months old Sahiwal calves were randomly allocated to four groups and fed a basal diet without any supplementation (control) or supplemented respectively with silymarin (500 mg/kg DM, T1), nano-zinc (40 mg/kg DM. T2), and both silymarin and nano-zinc (500 mg/kg DM + 40 mg/kg DM, T3) for 120 days of trial period. Blood was sampled on 0, 30, 60, 90, and 120 days of trial period for the analysis of protein metabolites. The mean protein level was significantly (P<0.05) higher in treatments than control groups but the level was observed highest statistically (P<0.05) in treatment that offered both silymarin and nano-zinc in the diet. However, no statistical difference in protein level was observed between T1 and T2. The mean plasma albumin and albumin concentration on 0, 30, 60, 90, and 120 days were statistically similar in each group. The mean plasma concentration of globulin was statistically (P<0.05) enhanced in the T3 group which is supplemented by silymarin and nano-zinc as compared to all other groups. The mean creatinine concentration was statistically (P<0.05) higher in the T2 and T3 as compared to control and T1 groups and no statistical difference observed between control and T1 groups. The mean plasma urea nitrogen and plasma urea nitrogen on all days of the study were statistical similar among groups, Result of the present study is concluded that dietary supplementation of silymarin and nano-zinc improved the function of kidney and immunity of Sahiwal growing calves.