Vol. 11, Special Issue 3 (2022)

Author(s):
Mridusmrita Buragohain, Abhijit Deka, Mousumi Hazarika, Shameem Ara Begum, Nibedita Tamuli, Amdedul Islam Mazumder, Rubi Devi Nath and Udaya Sai Sitaram Tella

Abstract:
A 6 years old, brown, male dog carcass was presented to the Department of pathology, College of Veterinary Science, Assam Agricultural University, Guwahati-22 for detailed post mortem examination with a clinical history of anorexia, lethargy, fever and gradual weight loss. Various hemato-biochemical parameters that have been estimated during the clinical phase of the disease showed extreme high concentration of blood urea nitrogen (BUN), bilirubin, ALT and AST, whereas blood profile revealed low level of hemoglobin (Hb), total erythrocyte count (TEC) and packed cell volume (PCV), which was indicative of anemia associated with renal dysfunction. At necropsy remarkable gross changes were observed only in kidneys and liver. The kidneys were noticeably large and pale and cut section revealed large, wide cortical area. Mild hepatomegaly with marked hepatic steatosis were observed throughout the hepatic surface. Microscopic examination of such kidneys revealed glomerular hypercellularity which completely occupying the Bowman’s space indicating acute glomerulonephritis. Focal areas of tubular degeneration and cellular swelling of the tubular epithelium were also noticed. In liver, severe hepatic steatosis was observed which was characterized by large numbers of fat vacuoles of varying size in the hepatocytes. The fat vacuoles displace the nucleus towards the periphery of cell.