Vol. 11, Special Issue 3 (2022)

Author(s):
Akhila MR, KA Bindu, Elizabeth Kurian, T Naicy, TV Aravindakshan, Siju Joseph and VL Gleeja

Abstract:
The current study involves the analysis of the exons 1, 2 and 14 of bovine ITGβ6 gene and identifies SNPs in association with FMD infection. DNA was extracted from the blood samples taken from crossbred cattle from FMD outbreak areas. PCR-SSCP was performed to identify SNPs in exon 1, 2 and 14. A non-synonymous SNP c.29G>A was identified in exon 2 while a synonymous SNP, c.133C>T was observed in exon 14. Statistical analysis revealed significant association of SNPs with FMD infection (p≤0.01) in crossbred cattle. The study indicates the potential role of ITGβ6 in FMD infection and hence offers a chance to explore the possibility of breeding for FMD resistance in future.