Toll Free Helpline (India): 1800 1234 070

Rest of World: +91-9810852116

Free Publication Certificate

Vol. 11, Special Issue 2 (2022)

Concurrent effects of experimental Escherichia coli infection and alpha-cypermethrin intoxication on biochemical parameters of broiler chicken

Author(s):
Priyanka Tank, KK Jakhar, Vikas Nehra and Diwakar Singh Rana
Abstract:
The poultry industry in India is a leading enterprise in the agriculture sector. On one hand where poultry farming can draw large benefit to the firms, conversely the farmers also have to deal with the bacterial and viral infections prevalent among the birds. Escherichia coli (E. coli) infection is a major bacterial cause of many localised and systemic infection in poultry. With the advent of newer ways of farming, pesticides have also gained much importance in the field. The leaching of these pesticides into the environment poses a great threat to public health as well as the animals. These pesticide residues synergise with the pathogenic effects of bacteria and potentiates in breaching the host immunity. The present study was undertaken with an aim to study the effects of experimentally alpha-cypermethrin intoxicated broiler chicken, co-infected with collibacillosis, on the biochemical parameters. A total number of one hundred and fifty day old chicks were taken for the experimental study. They were orally administered with 1/5th of maximal tolerated dose (i.e. 63.94 mg/kg. body weight) of alpha-cypermethrin through drops and concurrently infected with 107 CFU of E. coli in 1.0 ml normal saline solution via intra-peritoneal route. The serum of the birds was collected during slaughter for assessing the biochemical parameters. The biochemistry of the serum reflects the soundness of different organs in the body. Biochemical studies of the serum revealed a significant reduction in mean total protein and albumin concentration of both infected groups and alpha-cypermethrin intoxicated group as compared to control. However, serum AST, ALT, ALP and LDH showed significant increase in both infected groups and alpha-cypermethrin intoxicated group. Thus, alpha-cypermethrin toxicity (1/5th maximum tolerated dose) and E. coli infection significantly alters the serum biochemical profile.
Pages: 1423-1428  |  255 Views  55 Downloads
How to cite this article:
Priyanka Tank, KK Jakhar, Vikas Nehra and Diwakar Singh Rana. Concurrent effects of experimental Escherichia coli infection and alpha-cypermethrin intoxication on biochemical parameters of broiler chicken. The Pharma Innovation Journal. 2022; 11(2S): 1423-1428.

Call for book chapter