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Vol. 11, Special Issue 2 (2022)

Application of simulation tool for estimation of impeller power requirement in bioreactor

Author(s):
Sumit Mehta, PS Minz, Chitranayak and AD Vairat
Abstract:
Simulation tool was applied to determine various bioreactor design parameters viz impeller Reynolds’s number and impeller power requirement. Estimation of impeller power helps to design and select rotor drive assembly. Bioreactor with vertical cylindrical design and 10 litre capacity was used as initial design framework. Different ratios of height and diameter (H/D = 0.75, 0.9, 1.05, 1.20, 1.35 and 1.5) was considered in the simulation program. Power requirement was estimated for four different impeller designs (1, 2, 3 and 4) for a wide range of rotational speed (25, 50, 75, 100, 125, and 150 rpm). Impeller Reynolds’s number was found in transitional region for all the impeller 1, 2, 3 and 4 operating between 25 to 150 rpm. Impeller Reynolds’s number was in the range of 22 to 858 and estimated power requirement was in the range of 14 to 83.10 W for impeller speed 25-150 rpm.
Pages: 1027-1031  |  255 Views  95 Downloads
How to cite this article:
Sumit Mehta, PS Minz, Chitranayak and AD Vairat. Application of simulation tool for estimation of impeller power requirement in bioreactor. The Pharma Innovation Journal. 2022; 11(2S): 1027-1031.

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