Vol. 11, Special Issue 11 (2022)

Author(s):
Hemali Patel, Neha Rao, Nitin R Patel and Nilesh Gohil

Abstract:
The study was conducted to access haemato-biochemical changes and to evaluate the efficacy of adjuvant therapy in CPV affected dogs. The clinical signs were anorexia, haemorrhagic diarrhoea, dehydration, dullness and vomition. Thirty two dogs were randomly selected based on clinical signs and the results of immune-chromatographic (IC) test and divided into 4 groups for therapeutic management, viz., Group B, C, D and E, each of 8 animals, and a group of six healthy dogs (Group A) presented at Veterinary Clinical Complex for routine vaccination was kept as control. Group B dogs were treated with standard therapy. In groups C, D and E, along with standard therapy, honey, N-acetyl cysteine and Glutamine powder were given as adjuvant, respectively. Highly significant decrease in WBC count, lymphocytes, total protein and significant decrease in albumin, globulin, whereas neutrophils and creatinine were highly significantly increased and BUN was significantly increased in CPV infected dogs as compared to healthy dogs. The therapeutic efficacy based on haemato-biochemical parameters showed comparable findings between the different treatment protocols on day 5 as compared to values of healthy group. The recovery time was significantly less and recovery rate was highest in dogs treated with N-Acetyl Cysteine as adjuvant.