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Vol. 11, Special Issue 11 (2022)

Effect of repeated oral administration of butachlor on oxidative stress parameters and histopathological changes in wistar rats

Author(s):
Uzma Farooq S, Sharma A, Khajuria V, Singh A and Kour H
Abstract:
The experiment was conducted with wistar rats divided into two groups for a period of 28 days and was given through oral gavage. Group I served as control and was provided with water only for drinking purposes. Animals of Group II were administered Butachlor (Mancheter EC) @ 262 mg / kg B.W / P.O. Increase in lipid peroxidation and decrease in blood glutathione, glutathione peroxidase and transferase, catalase and superoxide dismutase in blood and tissues respectively revealed a clear picture of oxidative stress. Histopathologic ally, liver and kidney exhibited structural alterations as compared to control.
Pages: 417-422  |  162 Views  66 Downloads
How to cite this article:
Uzma Farooq S, Sharma A, Khajuria V, Singh A and Kour H. Effect of repeated oral administration of butachlor on oxidative stress parameters and histopathological changes in wistar rats. The Pharma Innovation Journal. 2022; 11(11S): 417-422.

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