Vol. 11, Special Issue 10 (2022)

Several cause factors affecting the pig population in India the infectious diseases are major one which are difficult to control in pig population. Pig population is affected by Classical swine fever (CSF) is one of the most life threatening viral diseases of domestic pigs and wild boar. Classical swine fever virus (CSFV), a member of the Pestivirus genus within the Flaviviridae family, is a highly contagious and very often fatal infection in pigs, which contributes to severe economic loss in pig farming. Though the several guidelines are recommended from the different state governments in order to mitigate the outbreaks, CSF remained underestimated and neglected for decades in India. In this aspect our country requires rapid and sensitive diagnostic tests for an early detection of infection to limit the spread of the disease. In the present study reported the outbreak of the CSF in the local domestic pigs in the Bidar district of Northern Karnataka, the affected animals were totally restless and there was conjunctivitis, very high body temperature, complete anorexia, cough and abnormal swaying movements, Pigs were huddled together in the corner of the house, exhibited labored breathing, staggering gait or swaying movement of the hindquarters and erythematous lesions in the abdominal region, ears and in the medial side of the legs, Conjunctivitis, thick ocular discharge and watery nasal discharge were also observed, followed by the sudden death of the animals were noticed. There was about 20-30 animals were dead over a period of 15 days with typical clinical symptoms every day one or two animal death were reported. Clinical samples like kidneys, lymph nodes, intestine, spleen, brain, heart, liver and lungs were collected and sent to South Regional Disease Diagnostic Laboratory (SRDDL) Institute of Animal Health and Veterinary Biologicals (IAH&VB) for the further analysis to find out the root cause by using molecular techniques. The outcome of the current study concludes that CSF viral strains circulating in the Bidar region of Karnataka are highly virulent, further the disease can be diagnosed specifically using molecular technique like RT-PCR and Post-mortem examination and clinical symptoms.