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Vol. 10, Special Issue 8 (2021)

Evaluation of acute oral toxicity of a phytogenic egg-laying stimulant

Author(s):
Sunil Hajare, Ranjit Suresh Ingole, Maheshkumar Vitthal Ingawale, Vivek Borekar and Bhaskar Ganguly
Abstract:
Achieving and maintaining optimum egg production levels is important for successful poultry layer enterprise. However, layer egg production is commonly affected due to various reasons such as endocrine or nutritional exhaustion, poor management and different types of diseases. Goldeg® (M/s Ayurvet Limited, India) is a phytogenic egg-laying stimulant that helps to achieve and restore optimum production levels in layers. A study was undertaken to evaluate the potential of Goldeg® to elicit acute oral toxicity as per OECD 423 guidelines. Nine non-pregnant, nulliparous, adult female Swiss albino mice were used for the study. Following the oral administration of the test substance, the animals were observed for the manifestation of toxic effects and mortality. Toxicity was evaluated on the basis of changes in body weight, overt signs of toxicity, gross and histological appearances of vital organs, and blood biochemistry. No toxic effects or mortalities were observed till day 14 and Goldeg® was found safe for oral use.
Pages: 664-666  |  244 Views  29 Downloads
How to cite this article:
Sunil Hajare, Ranjit Suresh Ingole, Maheshkumar Vitthal Ingawale, Vivek Borekar and Bhaskar Ganguly. Evaluation of acute oral toxicity of a phytogenic egg-laying stimulant. The Pharma Innovation Journal. 2021; 10(8S): 664-666.
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