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Vol. 10, Special Issue 8 (2021)

Clinical evaluation of multimodal analgesia for optimum post-operative pain management in dogs undergoing ovariohysterectomy

Author(s):
AA Mitra, Dr. MG Thorat, Dr. RV Raulkar, KN Tayade, AA Jadhav, KS Pawar, PD Salve and MB Pawar
Abstract:
The present study was conducted for clinical evaluation of different multimodal analgesia protocols for optimum post-operative pain management in 12 clinical cases of isoflurane anaesthetized dogs undergoing ovariohysterectomy. These dogs were randomly divided into two equal groups in which Group A received fentanyl, lignocaine and ketamine (FLK) CRI and Group B received buprenorphine, lignocaine and ketamine (BLK) CRI throughout the surgery, along with administration of carprofen before surgery as well as 24 and 48 hours after recovery. Quality of anaesthesia was satisfactory in both the groups. Extubation and recovery time was longer in group B along with mild sedation effect at recovery, while recovery was smooth in Group A. Isoflurane-sparing effect was greater in Group A as compared to Group B. The mean values of rectal temperature, heart rate and respiration rate at various intervals exhibited a significant decreasing trend in both the groups, but were within the normal physiological limit. The arterial blood pressure and SpO2 values of both the groups fluctuated significantly throughout the anaesthesia period and hemodynamic stability was well maintained in both the groups. The short form of Glasgow composite measure pain scale (GCMPS-SF) exhibited non-significant variation of pain in between the groups and both the groups showed decreasing pain scores upto 72 hours of surgery. No dog in any group required rescue analgesia. On the basis of observations, administration of FLK CRI and carprofen as multimodal analgesic along with isoflurane anaesthesia provided optimum analgesic effect than BLK CRI and carprofen for post-operative pain management in dogs undergoing ovariohysterectomy.
Pages: 505-510  |  519 Views  210 Downloads
How to cite this article:
AA Mitra, Dr. MG Thorat, Dr. RV Raulkar, KN Tayade, AA Jadhav, KS Pawar, PD Salve and MB Pawar. Clinical evaluation of multimodal analgesia for optimum post-operative pain management in dogs undergoing ovariohysterectomy. The Pharma Innovation Journal. 2021; 10(8S): 505-510.

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