Vol. 10, Special Issue 7 (2021)

Author(s):
RKR Sangamitra, G Suganya, V Leela, M Balagangadhara Thilagar

Abstract:
The study was performed to calculate the prothrombin time in dogs affected with parenchymal, biliary and neoplastic hepatic disorders compared with dogs which are apparently healthy. Twenty apparently healthy dogs formed the control group. Hepatic dysfunction dogs where classified as parenchymal disorder (9), biliary disorder (6) and neoplastic disorder (5) formed the experimental group. Since liver functions as a site of production and removal of coagulation proteins, the present study was done to measure the thrombin time in healthy as well as dogs in experimental group. The prolonged prothrombin time was significantly noticed in dogs affected with parenchymal and neoplastic disorders of experimental group when compared with control dogs whereas the no significant alteration was observed in biliary disorder dogs. Thus the results of this study suggest that there is a significant change in the prothrombin time in dogs with hepatic dysfunction and it could be a prognostic indicator for the haemostatic disorders in dogs.