Abstract:Sheep showing clinical signs of nasal discharges, coughing, fever and dullness were tentatively diagnosed as respiratory tract infections were included in the present study which were confirmed as respiratory diseases of bacterial origin through cultural examination. Screened sheep which were positive for
Mannheimia haemolytica were divided in to two groups for therapeutic study. Group-I (n=6) treated with ceftiofur sodium through standard intra muscular route and Group-II (n=6) nebulized with ceftiofur sodium diluted with normal saline (1:3) using piston type nebulizer @1.1 mg/kg bw for five days.
Sheep received nebulization therapy (Group-II) have shown significantly better clinical improvement and cure that of group –I which was evaluated in terms of remission of clinical signs, improved respiratory score and revival of haematological parameters like Hb, TLC and neutrophil count. Hence it is concluded that ceftofur sodium can be administered through aerosol route through nebulization in ailing sheep with promising results.