Vol. 10, Special Issue 1 (2021)

Author(s):
Chandrahas Sannat, SD Hirpurkar, Ragini Hazari, Sanjay Shakya, MO Kalim, Nidhi Rawat and Amit Kumar Gupta

Abstract:
Present investigation was made to study antibiogram profile of Methicillin Resistant Staphylococcus aureus (MRSA) of animal origin. MRSA isolates were obtained from bovine mastitis and wound infection of animals using cultural isolation and were confirmed by S. aureus specific thermonuclease (nuc) and MRSA specific mecA gene in PCR assay. A total of 13 MRSA isolates were obtained and subjected to antibiotic sensitivity test using 10 numbers of selected antibiotics by disc diffusion test. MRSA isolates exhibited variable degree of sensitivity towards various antibiotics. MRSA isolates were detected 100% senisitive to linezolid and imipenem followed by clindamycin (92.31%), tetracycline (76.92%), vancomycin and gentamycin (53.85%). Isolates showed higher rate of resistance towards amoxicillin (84.62%) and penicillin (76.92%). All the isolates were found resistant to cefoxitin and methicillin. It can be concluded from present study that isolates harbouring mecA/ MRSA gene have tendency to exhibit resistant towards multidrug and treatment option can be explored by studying antibiogram of MRSA of particular region.