Vol. 10, Special Issue 12 (2021)

Author(s):
Syed Suheb, V Mahesh and BN Nagaraja

Abstract:
The present study was undertaken with the objectives to study the influence of Pentosan Polysulfate Sodium on osteoarthritis in dogs thus the present study was conducted to study the influence of Pentosan Polysulfate Sodium on physiological, clinical, haematological, biochemical, synovial fluid and radiographic parameters in dogs with osteoarthritis. Study was carried out among the six dogs presented to Department of Veterinary Surgery and Radiology, Veterinary College Hospital, Hebbal, Bengaluru irrespective of breed, age and sex diagnosed with osteoarthritis of hip joint for a period of one year. The drug Pentosan Polysulfate Sodium administered at the dose rate of 3 mg per kg body weight by subcutaneous route at weekly intervals for four weeks. There were no significant variations observed in physiological, haematological and biochemical parameters. There was significant improvement in weight bearing in all the six dogs after the treatment. The drug Pentosan Polysulfate Sodium administered was found to be effective and best suited for the treatment of osteoarthritis in dogs.