Vol. 10, Special Issue 12 (2021)

Author(s):
TV Meenambigai and C Sworna Kumari

Abstract:
Bioprinting involves computational modeling, utilizes biomaterials, cells, and bioactive components as a “bioink” to fabricate prospective tissue structures in three-Dimensional (3D) printing. The printed product is heavily influenced by biomaterial parameters such as biocompatibility, cell viability, and the cellular microenvironment. Bioprinting provides control over cell placement and therefore creates a homogenous distribution of cells correlating to a uniform tissue in growth. This technology has already found success in human studies and developing in veterinary research, where a variety of functional tissues have been generated for both in vitro and in vivo applications. Various bioprinting technologies using Computer-Aided Design has been progressed in printing different types of tissue, including vasculature, heart, bone, cartilage, skin and liver. The development of such 3D in vitro systems has attracted increasing attention in human and veterinary healthcare predominantly driven to rectify the demand of a limited supply of organs and a demand for less expensive drug testing models.