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Vol. 10, Special Issue 11 (2021)

Heamato biochemical evaluation of induction combinations of romifidine guaifenesin ketamine and dexmedetomidine guaifenesin ketamine under isoflurane anesthesia in cattle

Author(s):
Kumar Swamy, Dilipkumar D, Venkatgiri and Vinay P Tikare
Abstract:
The study was conducted to evaluate the feasibility of romifidine and dexmedetomidine sedation for guaifenesin, ketamine-isoflurane general anaesthesia for various surgeries in cattle. The study was carried out in 12 clinical cases of cattle presented to Veterinary Clinical Complex, Veterinary College Bidar for various surgical procedures. The cases were randomly divided into two groups consisting of six cattle in each group. The animals of group I were administered with romifidine (10 µg/kg, IV). The animals of group II were administered with dexmedetomidine hydrochloride (2.5µg/kg, IV) immediately followed by guaifenesin (50 mg/kg, 5% sol). After ten minutes, the anaesthesia was induced by administering ketamine hydrochloride (3 mg/kg, I/V) and maintained with isoflurane (1-2%) in both the groups. Though the induction and recovery were smooth and uneventful in both groups, faster onset of sedation, faster down time to sternal recumbency, early recovery time to regain sternal position and to assume standing position were noticed in cattle premedicated with romifidine than in cattle premedicated with dexmedetomidine for guaifenesin-ketamine-isoflurane general anaesthesia Haemoglobin, packed cell volume, total erythrocyte count and total leukocyte count decreased non-significantly at maximum depth of anaesthesia in both the groups. Neutrophilia and relative lymphocytopenia was recorded in both the groups. Biochemical parameters decreased significantly towards the end of anaesthetic period in both the groups, however, it was within normal physiological limits. The present study showed romifidine-guaifenesin-ketamine-isoflurane combination was ideal to perform major surgeries in cattle without any haemato biochemical parameters complications.
Pages: 2015-2018  |  225 Views  66 Downloads
How to cite this article:
Kumar Swamy, Dilipkumar D, Venkatgiri and Vinay P Tikare. Heamato biochemical evaluation of induction combinations of romifidine guaifenesin ketamine and dexmedetomidine guaifenesin ketamine under isoflurane anesthesia in cattle. The Pharma Innovation Journal. 2021; 10(11S): 2015-2018.

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