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Vol. 10, Special Issue 11 (2021)

Standardization of dose of acepromazine as a sedative in buffalo calves

Author(s):
Vijay Nain, Sonu Devi, Umed Singh Mehra and Amit Kumar
Abstract:
In the present investigation, six experimental trials were undertaken on clinically healthy male buffalo calves (Bubalus bubalis), 5 to 10 months of age, and weighing 60 to 140 kg. Effect of acepromazine (0.05 mg/kg, i.m.), was evaluated in twelve animals. The calves were ataxic after 6.16±1.07 minutes and went into sternal recumbency in 74.16±22.28 minutes of drug administration. There was good sedation without analgesia. The animals were standing with ataxia after 131.5±17.80 minutes and complete recovery took 211.83±6.94 minutes of its administration. Significant hypotension (15%) and tachycardia were observed. In conclusion, acepromazine (0.05 mg/kg, I.M.) can be safely used for chemical restraint of normovolemic buffaloes.
Pages: 938-943  |  278 Views  83 Downloads
How to cite this article:
Vijay Nain, Sonu Devi, Umed Singh Mehra and Amit Kumar. Standardization of dose of acepromazine as a sedative in buffalo calves. The Pharma Innovation Journal. 2021; 10(11S): 938-943.

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