NAAS Rating: 5.23 new
Vol. 10, Special Issue 11 (2021)
Lipid lowering and antioxidant activity of flavonoid diosmin and hesperidin supplementation in donkeys
Suvidhi, LN Sankhala, Yash Pal, RA Legha, P Karela and RK Dedar
Hesperidin and diosmin are a naturally occurring flavonoid and reported for having hypolipidemic properties. In present study effects of oral supplementation of hesperidin and diosmin on serum lipid profile, serum biochemical and oxidative stress markers were investigated in adult Poitou female donkeys. Donkeys were divided in two groups having 6 donkeys in each group; first group was kept as control while second group was kept as treatment group. Oral supplementation of diosmin and hesperidin @ 10 mg/kg body weight was given to donkeys of treatment group. Serum total lipids, serum triglyceride and serum cholesterol levels were found significantly decreased in treatment group. Serum malondialdehyde levels were found significantly lower in the treatment group and serum glutathione was found significantly higher in the treatment group. Results of the study demonstrated that the oral supplementation of hesperidin and diosmin combination have lipid-lowering and antioxidant properties and have potential to be used therapeutically in donkeys.
How to cite this article:
Suvidhi, LN Sankhala, Yash Pal, RA Legha, P Karela and RK Dedar. Lipid lowering and antioxidant activity of flavonoid diosmin and hesperidin supplementation in donkeys. The Pharma Innovation Journal. 2021; 10(11S): 224-228.