Abstract: Human population is growing at a greater pace creating a huge gap between food production and population size. The difference between the two has somehow been managed with the huge utilization of pharmaceuticals be it in agriculture of in farm animals. These antibiotic residues have become a potential hazard for human as well as animal health and a great extent obstacle to export milk, meat and eggs. The consequence of these has shown a negative impact on human health ranging from food allergy to drug resistance. Judicious use of antibiotics and proper maintenance of withdrawal period is the only way to save the mankind from the rapid growing havoc of antibiotic residue in animal foods.