Conjugated linoleic acid (CLA): Implications for human health and animal production
Tony Jose and Alphine Joseph
Conjugated linolenic acid are isomers refer to a group of positional and geometric isomers of the omega-3 essential fatty acid α-linolenic acid (cis-9, cis-12, cis-15 C18:3, ALA). Its isomers can be either cis- and/or trans- and their double bonds are separated by a single bond. Food products from ruminants and some plant products are the major sources of CLA. The isomers in ruminants arise as a result of bacterial isomerization of ALA in the rumen. The concentration of CLA isomers in seed oils is higher than in milk and edible parts of ruminant carcass. The CLA isomers from the plant sources are in the form of conjugated trienes, whereas those in ruminant products are of conjugated diene type. Some plant seed oils are the richest natural sources of CLA isomers. So, searching for methods of increasing the CLA isomer content in food of animal origin not exhibiting negative effects on animal welfare and physiology is very important for researchers. A presence of long-chain and very long-chain conjugated unsaturated fatty acids was also confirmed in some ruminant tissues. Clinical studies documented that health-promoting properties have been attributed to CLA isomers. It was also evidenced that animal diet may influence the CLA synthesis. The proper identification of geometric and positional isomers of conjugated unsaturated fatty acids in biological samples is a great challenge in research field.
How to cite this article:
Tony Jose and Alphine Joseph. Conjugated linoleic acid (CLA): Implications for human health and animal production. The Pharma Innovation Journal. 2020; 9(8S): 33-37.