Vol. 9, Special Issue 7 (2020)

Author(s):
Sreeranjini AR, Ashok N, Maya S, Lucy KM and Chungath JJ

Abstract:
The present study was conducted on the pancreases of goats collected from second to fifth month of prenatal life. Tissue pieces were fixed in 10% Neutral buffered formalin, processed, sectioned, examined under light microscope and the images were recorded digitally. Vasculogenesis within the mesenchyme of pancreas was evidenced in 58 days-old foetuses. By 69 days of development, more vessels could be noticed indicating angiogenesis. Accumulation of blood cells was found within the central part of a few developing, large islets of Langerhans. In 70 days-old foetuses, small blood vessels and blood cells were noticed in the capsule and within the islets. In foetuses of 91 days age blood-filled spaces were seen among the endocrine cells of some larger islets. After 105 days, arterioles and venules could be differentiated among acini along with ducts of varying size, nerve bundles and isolated neurons. In 140 days-old foetuses, sinuses were seen in most of the large islets. By 148 days, within most of the lobules a central trunk of blood vessels, peri-vascular plexuses, intralobular ducts and peri-ductular plexuses were noticed. In addition, blood vessels were observed in the interlobular septa along with ducts, nerve bundles and ganglia. The present study indicated that vasculogenesis was initiated in the pancreas of goats during early prenatal life itself and angiogenesis progressed throughout prenatal life corresponding with advancement in the development of exocrine and endocrine components.