Vol. 9, Special Issue 4 (2020)
Lithium antimony thiomalate and acyclovir therapy for buffalo mammillitis
Mammillitis is a condition in she buffaloes in which there will be sudden teat inflammation, enlargement, difficulty in milking, difficult for the calf to suckle, formation of black necrotic patches with circumscribed necrotic areas on teat base. The affected teat slough off in primiparous buffaloes and the cause is suspected to be by Herpes virus. Ten buffaloes exhibiting mammillitis were treated with three injections of lithium antimony thiomalate (2 mg/kg deep IM), acyclorir (1-1.5 mg/kg slow IV in fluid), chlorophenaramine maleate (0.5-1.0 mg/kg IM),meloxicam (0.5- 1 mg/kg, IM) with two days apart along with external application of ointment containing acyclovir. Clinical recovery was seen in 8 buffaloes after 7 days of last dose of treatment. The hyperemic and edematous teats noticed earlier before treatment slowly resolved to almost normal size. Thus, the efficacy of lithium antimony thiomalate, acyclovir, chlorphenaramine meleate and meloxicam may be attributed to anti-fibrosis, antiviral, anti-allergic and anti inflammatory effect respectively in buffalo mammillitis.
How to cite this article:
NB Shridhar. Lithium antimony thiomalate and acyclovir therapy for buffalo mammillitis. The Pharma Innovation Journal. 2020; 9(4S): 49-52.