Therapeutic studies on benign prostatic hyperplasia in canines
Author(s):
Rani RN, Renukaradhya GJ, Sahadev A, PT Ramesh, GP Kalmath and Suchitra BR
Abstract:
The present study was conducted on 12 intact male dogs with clinical symptoms related to benign prostatic hyperplasia (BPH) and 12 apparently healthy intact male dogs presented to the Department of Veterinary Gynaecology and Obstetrics, Veterinary College, Hebbal, Bengaluru. Presumptive diagnosis was done based on history, clinical signs, digital rectal palpation of prostate and ultrasonographic measurement of prostatic volume. On haemato-biochemical analysis, TEC and PCV in BPH affected dogs were significantly lower compared to healthy dogs whereas other parameters did not vary between healthy and BPH affected dogs. Dogs with BPH were categorised into two treatment groups as Group I (n=6), treated with finasteride (0.1-0.5 mg/kg, SID, PO) and Group II (n=6) treated with flutamide (5 mg/kg, SID, PO) for 45 days. Dogs were re-examined on day 15, 30, 45 and 60 to evaluate response to the treatment. The results revealed that both medications were effective to resolve clinical signs and decrease prostatic volume.
How to cite this article:
Rani RN, Renukaradhya GJ, Sahadev A, PT Ramesh, GP Kalmath, Suchitra BR. Therapeutic studies on benign prostatic hyperplasia in canines. Pharma Innovation 2024;13(3):22-26.