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Vol. 12, Issue 4 (2023)

Analyses of combination chemotherapy effectiveness for canine transmissible venereal tumor in 188 indigenous dogs

Author(s):
A Sabarinathan, Chhavi Gupta, A Thangamani, A Ganesan, M Balagangatharathilagar and Dr. V Prabaharan
Abstract:
Canine transmissible venereal tumor occurs in sexually active dogs of tropical and subtropical region. The tumor is of near constant karyotypic variation of 58-59 chromosomes against the normal chromosomes number of 78 in dogs. Southern district of Tamil Nadu state is well known for the pure germplasm of indigenous dog breeds namely, Chippiparai, Kanni, Rajapalayam and Kombai such indigenous breeds were more prone for the Canine Transmissible Venereal Tumor (CTVT). The study was carried out in 188 indigenous dogs confirmed with CTVT. In Group I 94 dogs were treated with Inj. Vincristine sulfate @ 0.025 mg per kg b.wt via Intravenous (IV) route at 7 days interval 4-8 doses. In group II 94 dogs were treated with Inj. Vincristine sulfate @ 0.025 mg per kg b.wt via Intravenous (IV) route along with Inj. Ivermectin @ 200 mcg per kg b.wt subcutaneous (SC) at 7 days interval 4-6 doses.
Pages: 2700-2702  |  340 Views  176 Downloads


The Pharma Innovation Journal
How to cite this article:
A Sabarinathan, Chhavi Gupta, A Thangamani, A Ganesan, M Balagangatharathilagar, Dr. V Prabaharan. Analyses of combination chemotherapy effectiveness for canine transmissible venereal tumor in 188 indigenous dogs. Pharma Innovation 2023;12(4):2700-2702.

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