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Vol. 12, Issue 4 (2023)

Comparative evaluation of wound healing in mice treated with betadine ointment and collagen granules

Author(s):
Analisha Debbarma, Indramani Nath, Sidhartha Sankar Behera, Smruti Ranjan Mishra, Susen Kumar Panda and Ritun Patra
Abstract:
The study was conducted on 18 Swiss albino mice to determine the potency of betadine and collagen granules in wound healing. Two groups were made, i.e., Group-I (treated with betadine ointment) and Group-II (treated with collagen granules), each group containing 9 mice. An intraperitoneal injection of a mixture of 12.5 mg/kg of xylazine hydrochloride and 80 mg/kg of ketamine hydrochloride was used to induce anaesthesia, and a wound was created with the help of a 5mm biopsy punch on the dorsal area. On average, 17.8 ± 0.43 days in Group-I and 17.5 ± 0.42 days in Group-II were required for complete healing. The wound contraction area was 5.03 ± 0.06 mm, 4.40 ± 0.09 mm, and 3.88 ± 0.05 mm in Group-I and 4.85 ± 0.06 mm, 3.98 ± 0.06 mm, and 2.93 ± 0.04 mm in Group-II, respectively, on the 3rd, 7th, and 14th days. And collagen granules supplement show a faster healing process than betadine-treated wounds.
Pages: 590-591  |  132 Views  56 Downloads


The Pharma Innovation Journal
How to cite this article:
Analisha Debbarma, Indramani Nath, Sidhartha Sankar Behera, Smruti Ranjan Mishra, Susen Kumar Panda, Ritun Patra. Comparative evaluation of wound healing in mice treated with betadine ointment and collagen granules. Pharma Innovation 2023;12(4):590-591.

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