Vol. 12, Issue 1 (2023)

Author(s):
Shweta Dhanda

Abstract:
CRISPR systems are a collection of adaptable gene-editing tools that perform a variety of ground-breaking tasks in a variety of application areas, including agricultural practices, the food industry, biotechnology, biomedicine, and clinical research. Particularly, the CRISPR/Cas9 technology has been widely and successfully used to combat human infectious viruses as the preferred new antiviral strategy. Human immunodeficiency virus (HIV), hepatitis B virus (HBV), human papillomavirus (HPV), and other viruses continue to pose a threat on a global scale and are likely to result in pandemics. The CRISPR/Cas9 system has already been modified to give host animals new antiviral powers by either changing the host genome or by specifically targeting viral intrinsic components in the form of DNA. This technology shows considerable potential for the treatment of human viral infectious illnesses, despite a number of restrictions and challenges that still need to be overcome. In this article brief biological overview of CRISPR/Cas9 systems and its applications to fight a variety of human infectious viruses was discussed.