Vol. 10, Issue 9 (2021)

Author(s):
Mahesh S Dhas, MK Patil, SP Awandkar, AA Deshmukh and MA Khan

Abstract:
The need of the plant derived medicine for the animal and human use in recent years is so much increasing. In present study the antibacterial property of Ficus racemosa leaf extracts having the four solvents ie. Aqueous, chloroform, methanol and acetone were evaluated using the disc diffusion method against the test bacteria Escherichia coli; 10mg, 20mg and 50mg concentrations were taken, the standard antibiotic used were Gentamicin (50 µg). Qualitative phytochemical analysis of four extracts and the extract having most potent antibacterial activity was evaluated using Liquid chromatography-mass spectrometry method for phytochemicals. In disc diffusion method the Aqueous extract was found to be most potent as showed highest zone of inhibition as compared to the other extracts against Escherichia coli. Liquid chromatography-mass spectrometry analysis of Aqueous extract showed presence of eleven phytochemical compounds, which could be the probable cause of the present antibacterial activity.