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Vol. 10, Issue 7 (2021)

Comparative evaluation of anatomical vs non-anatomical bone excavation in rabbit long bone defect model

Author(s):
Kalaiselvan Elangovan, Swapan Kumar Maiti, Shivaraju Shivaramu, Amitha Banu S, Divya Mohan and Naveen Kumar
Abstract:
Successful sample collection is an obligatory step in the biomedical research. It is well known that choosing right pre-processing sample collection techniques can improve effectiveness of result to a far extent. We experimentally compared two techniques of sample collection namely group A: Non-anatomical de-muscling and group B: Anatomical dissective de-muscling. Each group comprising of 10 animals undergone critical size (15mm) defects (CSD) in the radius, forming a defective long bone rabbit model. We found that a technique employing an anatomical dissective sample collection has faster sample excavation time without much requirement for post-excavation de-muscling. Based on the results obtained, this study concludes that the anatomical dissective approach of sample collection is a better collection method comparing with that of non-anatomical dissective sample collection. Other comparative diagnostic and biomechanical testing is the future arena of research on sample collection and evaluation.
Pages: 834-837  |  209 Views  45 Downloads


The Pharma Innovation Journal
How to cite this article:
Kalaiselvan Elangovan, Swapan Kumar Maiti, Shivaraju Shivaramu, Amitha Banu S, Divya Mohan, Naveen Kumar. Comparative evaluation of anatomical vs non-anatomical bone excavation in rabbit long bone defect model. Pharma Innovation 2021;10(7):834-837.
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