Comparative evaluation of anatomical vs non-anatomical bone excavation in rabbit long bone defect model
Kalaiselvan Elangovan, Swapan Kumar Maiti, Shivaraju Shivaramu, Amitha Banu S, Divya Mohan and Naveen Kumar
Successful sample collection is an obligatory step in the biomedical research. It is well known that choosing right pre-processing sample collection techniques can improve effectiveness of result to a far extent. We experimentally compared two techniques of sample collection namely group A: Non-anatomical de-muscling and group B: Anatomical dissective de-muscling. Each group comprising of 10 animals undergone critical size (15mm) defects (CSD) in the radius, forming a defective long bone rabbit model. We found that a technique employing an anatomical dissective sample collection has faster sample excavation time without much requirement for post-excavation de-muscling. Based on the results obtained, this study concludes that the anatomical dissective approach of sample collection is a better collection method comparing with that of non-anatomical dissective sample collection. Other comparative diagnostic and biomechanical testing is the future arena of research on sample collection and evaluation.
How to cite this article:
Kalaiselvan Elangovan, Swapan Kumar Maiti, Shivaraju Shivaramu, Amitha Banu S, Divya Mohan, Naveen Kumar. Comparative evaluation of anatomical vs non-anatomical bone excavation in rabbit long bone defect model. Pharma Innovation 2021;10(7):834-837.