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Vol. 10, Issue 7 (2021)

Ameliorative effect of quercetin on body weights and haematology of glyphosate induced toxicity in albino Wistar rats

Author(s):
P Manaswini Reddy, M Jeevanalatha, M Lakshman, B Kalakumar, Y Ravi Kumar and K Aparna
Abstract:
The ameliorative potential of Quercetin was studied against Glyphosate induced toxicity. Total 24 male Wistar rats were separated into four groups (n = 4). Group 1 (control) and groups 2, 3, 4 were received glyphosate, quercetin, glyphosate and quercetin at the rate of 600, 80, 600 and 80 mg/kg b.wt respectively orally for 14 days. All the animals were sacrificed on 15th day and evaluated for haematological alterations.
In the present study, Weekly body weight gains were significantly (P< 0.05) decreased in group 2 rats when compared to group 1. In group 4, there was a significant increase in body weights on 14th day of experiment when compared to group 2 rats. In group 2 Total erythrocytic count, Haemoglobin were significantly (P< 0.05) reduced and Packed cell volume, Total leucocytic count were increased which were ameliorated in group 4 rats. In conclusion, quercetin was found to possess moderate protective action against glyphosate induced toxicity.
Pages: 782-785  |  269 Views  30 Downloads


The Pharma Innovation Journal
How to cite this article:
P Manaswini Reddy, M Jeevanalatha, M Lakshman, B Kalakumar, Y Ravi Kumar, K Aparna. Ameliorative effect of quercetin on body weights and haematology of glyphosate induced toxicity in albino Wistar rats. Pharma Innovation 2021;10(7):782-785.
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