Vol. 10, Issue 5 (2021)

Author(s):
Dr. Satyabrat Dutta, Dr. Richa Sarkar, Dr. Kaushik Poran Bordoloi, Dr. Champak Deka and Dr. Palash Jyoti Sonowal

Abstract:
Antimicrobials or antibiotics are one of the most fruitful forms of therapy against pathogenic microbial infection however their broad and frequently indiscriminate use resulted in a widespread antimicrobial resistance that has caused a significant threat to public health and environmental security. Therefore, implementation of a substitute but potent effective ways to kill pathogenic bacteria and reduce the environmental risks are urgently needed. As a unique century-old natural remedies, bacteriophage (phage) therapy has a high efficiency in detecting and killing pathogenic microorganism in numerous environmental or ecological systems. Phages are the viruses which usually target and cause lysis of bacteria naturally without any antagonistic effect on human or animal bodies. For this reason, many scientists across the world have proposed that they can be used, alone or together with typical antibiotics, to treat pathological conditions. The increasing risk of antimicrobial resistance has revived the interest on Phage therapy. The main motive of this article is to provide a brief but comprehensive review of all aspects of natural phage therapy to counter the antibiotic resistance on a global scale.