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Journal code(s)
- E-ISSN Number: 2277-7695
- P-ISSN Number: 2349-8242
- CODEN Code: PIHNBQ
- ZDB-Number: 2663038-2
- IC Journal ID: 7725
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Vol. 10, Issue 4 (2021)
C-H-Activation approach in the synthesis of palonosetron core: A 5-HT3 receptor antagonist
Author(s):
Vivek K Mishra and Martin E Maier
Vivek K Mishra and Martin E Maier
Abstract:
Intramolecular rhodium (III) catalyzed annulation of benzamide 8 has been described in the efficient synthesis of palonosetron core, 5-HT3 receptor antagonists. C–H-activation enabled the simultaneous generation of rings B and C, which can further be functionalized to access a series alkaloid.
Intramolecular rhodium (III) catalyzed annulation of benzamide 8 has been described in the efficient synthesis of palonosetron core, 5-HT3 receptor antagonists. C–H-activation enabled the simultaneous generation of rings B and C, which can further be functionalized to access a series alkaloid.
Pages: 22-25 | 736 Views 151 Downloads
How to cite this article:
Vivek K Mishra, Martin E Maier. C-H-Activation approach in the synthesis of palonosetron core: A 5-HT3 receptor antagonist. Pharma Innovation 2021;10(4):22-25. DOI: 10.22271/tpi.2021.v10.i4a.7386
Journal code(s)
- E-ISSN Number: 2277-7695
- P-ISSN Number: 2349-8242
- CODEN Code: PIHNBQ
- ZDB-Number: 2663038-2
- IC Journal ID: 7725
Main Menu
Special Issue
Copyright Form
Identifier
The Pharma Innovation Journal
