Vol. 10, Issue 2 (2021)

Author(s):
Sudhanshu Pratap Singh, Ankesh Kumar, Prakrutik Bhavsar, Maitri Bhavsar, Nitu Sourya, Avaneesh Kumar Singh and Mukesh Sahu

Abstract:
Reproduction in the animals is the most important factor that not only affect the dairy farm profitability and the development of national economy but also it improves the living standard of rural and urban societies. Repeat breeding is a considerable problem in cattle breeding which leads to large economic losses due to increasing in the number of inseminations, increasing in the length of calving interval and moreover increasing in culling rates. A repeat breeder is generally defined as any cow that has not conceived after three or more services associated with true estrus. Gynaecological maneuvers induce inflammation and stress in animal which causes the releases of prostaglandins. Prostaglandins (PGF2α) is responsible for luteolysis, which may lead to decrease in progesterone level and the pregnancy is in compromised state. NSAIDs inhibit cyclooxygenase (COX) and thereby inhibits the synthesis of prostaglandins. This is how NSAIDs can be used for pregnancy maintenance.