Vol. 10, Issue 11 (2021)

Author(s):
Dr. Poonam Gupta

Abstract:
Risperidone is a typical orally active antipsychotic agent for bipolar disorders. It belongs to the chemical class of benzisoxazole derivatives and chemically, it is 4-[2-[4-(6-fluorobenzo[d]isoxazol-3-yl)-1-piperidyl] ethyl]-3-methyl-2, 6 diazabicyclo [4.4.0] deca-1, 3-dien-5-one. European pharmacopeia related substances A, B, C, D, E and G and others (impurities) have been obtained during its synthesis. The present work describes the detection, origin, synthesis, characterization and control of the related substances, which may improve the commercial process.