Vol. 9, Issue 8 (2020)

Methods: 30 eligible patients of Erectile Dysfunction with IIEF-15 Score < 24were enrolled in an open, single arm, pre and post, exploratory clinical trial with 4 weeks treatment duration. The test drug Dawa-ul-Khasak, with a dose of 7gms twice a day given. The effect of the study was assessed subjective and objectively in different follow ups. Patients were assessed for improvement in erectile function and sexual quality of life by using IIEF-15 Score and SQoL-M Scales respectively every 14^thand 28^thday of treatment. Patients were also assessed for subjective parameter on 7^th, 14^th, 21^st and 28^th day of study.

Results: The Mean ± SD of variable Erectile Function (EF), Orgasmic Function (OF), Sexual Desire (SD), Intercourse Satisfaction (IS) and Overall Satisfaction (OS) at 0 daywere 14.43±3.65, 5.57±2.13, 5.43±1.33, 6.90±1.99 and 4.50±1.25 respectively; while it was increases to 23.37±3.47, 7.67±1.65, 6.97±1.56, 10.33±2.56 and 7.27±1.05 respectively;at 28^th day of the study with highly significant ‘p’ value of <0.001. The Mean ± SD of the Sexual Quality of Life-Male Questionnaire at 0 day was 33.27±12.41 while it was 48.98±12.32at 14^thday and 57.87±11.40 at 28^thday. Significant statistical difference in IIEF-15 Score and SQol-M Questionnaire was observed in improving erectile function at 14^thand 28^thday (p< 0.001).

Interpretation and Conclusion: Based on the observation of the results of the study, it can be concluded that Dawa-ul-khasak is effective in the management of ED.