Vol. 9, Issue 7 (2020)

Author(s):
K Naga Rani, Shaik Rahman, D Kavitha, P Suseela and P Venkateswara Rao

Abstract:
Study the effect of Trichosanthes cucumerina and carica papaya on increasing platelet count by using rats models. Prepared the aqueous extract juice of fruit Trichosanthes cucumerina and carica papaya and studied the preliminary phytochemical analysis of extract. Studied the preliminary phytochemical analysis of extract fruit of Trichosanthes cucumerina and carica papaya and studied the Anti-platelet activity on aqueous extract juice. The cyclophosphamide studies was determined the low platelet count was shown by monocyte was decreased condition when compare to normal groups. In these platelet activation in trichosanthe cucumerina was increasing the platelet count, R.B.C, leukocytes, hemoglobin are totally increased when compare to normal and cyclophosphamide groups. Carica papaya shows it’s activity similler to Trichosanthes cucumerina activity. when compare to normal and cyclophosphamide groups cyclophosphamide and Carica papaya at low dose also shows increased activity in some parameters like R.B.C, platelet count leukocytes, hemoglobin, lymphocytes but its activity is less than cyclophosphamide and Carica papaya, Trichosanthes cucumerina high dose.