Vol. 9, Issue 7 (2020)

Author(s):
K Naga Rani, M Swapna, K Pavani, K Jyothsna, K Divya and P Venkateswara Rao

Abstract:
The aim of the present investigation is to evaluate the effect of anti-obesity activity of Sataria italica on rats by using food induced obesity method. To prepare the extract of Sataria italic (Fox-Tail millets), using ethanol as solvent & to study the anti-obesity activity of extract of Sataria italica using food induced obesity method. In this study checked the anti-obesity parameters like Low density protein cholesterol (LDL), High density protein cholesterol (HDL), Percentage of fat (PF), Waist circumference (WC), Body mass index (BMI), Total cholesterol level. In The present study whole grain extract of Setaria Italica has shown promising results in experimental anti-obesity. The extract of Setaria Italica showed the results for increased that the standard Orlistat drug, it indicates the test extract posses anti-obesity activity. The investigations of whole grain extract of Setaria Italica (150 mg/kg and 300 mg/kg) in both FST and TST models in rats were showed in vivo anti-obesity activity. In this study the results were obtained increased such as orlistat. So it is concluded that whole grain extract of Setaria italica should possessed the anti-obesity activity.